In a recent trial that lasted for four months, researchers found that ejaculatory problems resulting from hypogonadism, or low testosterone did not always subside from using testosterone replacement therapy. The senior author of the trial, Dr. Basaria explains how he, along with this team wanted to comprehensively study the effects on ejaculatory problems stemming from low testosterone from testosterone replacement therapy.
According to Dr. Basaria, male sexual dysfunction complications usually fall into one of three categories, erectile problems, ejaculatory complications, and libido issues.
The subject group consisted of 76 men with similar ejaculatory dysfunction symptoms including reduced ejaculatory volume, delayed ejaculation and the inability to ejaculate altogether.
All 76 subjects were confirmed to have low testosterone to qualify for the study, whilst they were also assessed for pelvic diseases, prostate cancer history, and the possibility of them taking certain drugs that are known to affect ejaculation in one way or the other. Furthermore, the team ensured that none of the subjects suffer from erectile dysfunction because unknown to most people, ejaculatory complications can occur even without erectile dysfunction.
During the trial, men were randomly selected to be given 60 mg of testosterone once a day, whilsts others were given a placebo.
During the four-month period, these men were periodically blood tested to measure testosterone levels, whilst also providing semen samples. Some of the men had agreed to at least attempt sex four times a month with their partners. The subjects were obliged to keep a log of all sexual activity including self-pleasure.
The team learned that by the end of this study, the group of men that actually received testosterone replacement therapy did have an increased amount of the hormone in their bodies. Unfortunately, ejaculatory volume did not improve all that much in this group, nor did it improve in the men who were administered placebo.
On the plus side, groups, the testosterone administered and the placebo administered showed varying amounts of improvements in terms of ejaculatory dysfunction. But in the grand scale of things, the minute differences between the groups were not all that impressive.
Prior to this trial, the evidence connecting low testosterone to ejaculatory dysfunction relied on measurements taken at one single point in time. This meant that it was unclear if low testosterone was responsible for this condition.
According to Dr. Basaria, this study clearly demonstrates that an androgen deficiency doesn’t necessarily have to be the main cause of ejaculatory dysfunction in the majority of cases. This study has its fair share of opponents who believe that a four-month control study is not long enough to ascertain the whole picture.
It is possible that this study can be a precursor to many further studies exploring the causes of ejaculatory dysfunction according to Dr. Basaria. He urges caution when it comes to using testosterone replacement therapy and strongly recommends its usage only in extreme circumstances.
Alternatives to Testosterone Replacement Therapy
There has been much debate about whether it is possible to have a viable alternative to testosterone replacement therapy. After all, testosterone replacement therapy is known to cause a number of potentially life-threatening side-effects. And these side-effects have been under the media spotlight particularly in the last two years. There has been a string of litigation, as well as bad press surrounding these treatments.
Some endocrinologists seem to suggest that natural testosterone supplements may be the answer. Natural testosterone supplements work by encouraging the body to start producing more of its own hormone, as opposed to administering synthetic versions. Natural testosterone supplements are relatively side-effect free when compared to testosterone replacement therapy. They are created from natural ingredients, some of which have demonstrated in clinical trials the positive influences on testosterone.